Brian Shoemaker and Nancy Van Schooenderwoert offer their book “Agile Methods for Safety-Critical Systems: A Primer Using Medical Device Examples.” This book, packed with real-world insights and direct experiences, is for managers who want the benefits of Agile but also must address regulatory compliance, integration of software with other disciplines, and product safety. In it, we combine our understanding of Agile development, hardware/software integration, and regulatory requirements. We know that Agile is simple but not easy; leadership is crucial to make this change spread. We show how to navigate the transition.